In the eighth season of the TV show Charmed, Cuoco appeared as Billie Jenkins, a powerful young witch with the powers of telekinesis and projection.Executive producer Brad Kern stated that Cuoco's character was initially brought in as a possible spin-off. Prior to the 2010–2011 season, she earned ,000 an episode for the series, the same as her co-stars.That October, Brown caused controversy within both of her parents' families when she announced her engagement to Nick Gordon, a man she previously considered her "big brother".When the couple announced they were married, her father's lawyer released a statement disputing the report.Brown was 14 when her parents divorced and Houston gained custody.When Houston died in February 2012, Brown was named as the sole beneficiary of her mother's estate.
and in the film The Hollow at the same time She also voiced the character of Brandy Harrington, a 14-year-old anthropomorphic mixed-breed dog, on the Disney Channel cartoon Brandy and Mr. Cuoco voiced the character of Kirstee Smith in Bratz from 2004 to 2005.
A video of the event was posted on You Tube and became a viral success.
She played a minor role in the Prison Break episodes "The Message" and "Chicago", as well as starring in the comedy horror spoof Killer Movie in 2008. In 2011, Cuoco appeared in Allure magazine's annual "Naked Truth" feature.
In October 2017, Cuoco founded Yes, Norman Productions, a film and television production company which entered an exclusive multi-year first look production deal with Warner Bros. The company optioned the rights to The Flight Attendant, a book written by author Chris Bohjalian, which will be developed into an limited series, with Cuoco to star and executive produce.
While working on The Big Bang Theory, Cuoco privately dated co-star Johnny Galecki for roughly two years until December 2009, while their characters on the show were also dating.